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Select best correct options to fill up the blanks.
(I) With repeated use of drugs, the tolerance level of receptors present in the body can ________
(II) Smoking produces ________ and reduces the concentration of ________ in blood.
(III) Cannabinoid receptors are present in the ________
(IV) Morphine is a very effective ________
(V) Opioids are extracted from the ________

A
(i) decreases, (ii) sedative, pain killer in brain, (iv) hallucinogen, depressants
B
(i) increase, (ii) CO, haemobound oxygen, (iii) brain, (iv) sedative, pain killer, (v) latex
C
(i) decreases, (ii) CO, haemobound oxygen, (iii) brain, (iv) sedative, painkiller, (v) latex
D
(i) increases, (ii) CO, haemobound oxygen, (iii) brain, (iv) sedative, painkiller, (v) resin
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