MediumNEET TEST
+4 / -1
Due to a mutation, a yeast cell produces defective RNA polymerase III. What will be its most likely consequence?
A
Synthesis of 5.8S rRNA in it will stop.
B
The catalytic RNA will not be produced inside its mitochondria.
C
Polypeptide synthesis in cytoplasm will not take place.
D
Polynucleotide synthesis in nucleus will be compromised.
Explanation
RNA polymerase III is responsible for transcription of tRNA, 5srRNA and snRNAs in eukaryotes. tRNA is essential for reading the genetic code and bringing the correct amino acids to the ribosome during translation (synthesis of polypetides). If RNA polymerase III is defective, the cell cannot produce tRNAs. Without tRNAs, the "translation machinery" cannot function, and the synthesis of polypeptides (proteins) in the cytoplasm will stop.
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