MediumNEET 2026
+4 / -1
The sixth mutant codon of beta globin gene causing polymerization of Haemoglobin and change in RBC shape is:
A
AGA
B
AUG
C
GUG
D
GAG
Explanation
In sickle-cell anaemia, the sixth codon of the β-globin gene changes from GAG (glutamic acid) to GUG (valine), causing haemoglobin polymerization and sickling of RBCs.
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